Chronology
- 1753 George Washington crosses the Allegheny River.
- 1773 James O'Hara purchases land that will become The Strip District.
- 1787 Pittsburgh Academy incorporated. Direct ancestor of the University of Pittsburgh.

- 1806 Last duel in Pennsylvania takes place in Oakland.
- 1814 Lawrenceville established by William Barclay Foster.
- 1814 U.S. Government purchases 30 acres in Lawrenceville for an arsenal.
- 1826 Stephen Collins Foster born in Lawrenceville July 4.
- 1829 Terminal for goods transported on the Pennsylvania Canal built at 11th Street in The Strip.
- 1834 Lawrenceville becomes a borough.
- 1837 The land now known as The Strip District annexed by the city of Pittsburgh.
- 1842 Mary Croghan elopes with Capt. Edward Schenley.
- 1844 Allegheny Cemetery opens.
- 1857 Louise Whitfield Carnegie born in New York City March 7.
- 1862 Enormous explosion kills 79 at the Allegheny Arsenal September 17.
- 1864 Stephen Collins Foster dies in New York City, NY January 13.
- 1866 Oakland Township incorporated.
- 1867 Architect Henry Hornbostel born in Brooklyn, New York.
- 1868 Lawrenceville annexed by the city of Pittsburgh.
- 1868 Oakland Township annexed to the City of Pittsburgh.
- 1874 Honus Wagner born in Carnegie (then Mansfield) February 24.
- 1879 Robert Lee Vann born in North Carolina August 27.
- 1886 Father James R. Cox born in Lawrenceville March 7.
- 1889 The birth of Schenley Park.
- 1893 Opening of Phipps Conservatory.
- 1894 Boxer Harry Greb born in Garfield June 7.
- 1895 Irene Kaufmann Settlement originated.
- 1895 Dedication of Carnegie Library November 5.

- 1900 Carnegie Institute of Technology founded.
- 1909 Forbes Field built.
- 1910 Pittsburgh Courier incorporated March 10.
- 1913 Boxer Fritzie Zivic born in Lawrenceville.
- 1913 Mellon Institute founded.
- 1923 Boys' Club of Pittsburgh organized March 21.
- 1926 Boxer Harry Greb dies in Atlantic City, NJ October 22.
- 1928 Fred Rogers born in Latrobe, PA, March 20.
- 1931 Kay Boys' Club established.
- 1933 Pittsburgh Crawfords Negro National League Champions.
- 1934 Roberto Clemente born in Carolina, Puerto Rico August 18.
- 1935 Pittsburgh Crawfords Negro National League Champions.
- 1936 Pittsburgh Crawfords Negro National League Champions.
- 1937 Homestead Grays Negro National League Champions.
- 1938 Homestead Grays Negro National League Champions.
- 1939 Homestead Grays Negro National League Champions.
- 1940 Homestead Grays Negro National League Champions.
- 1940 Robert Lee Vann dies October 24.
- 1941 Homestead Grays Negro National League Champions.
- 1942 Homestead Grays Negro National League Champions.
- 1943 Homestead Grays Negro National League Champions.
- 1944 Homestead Grays Negro National League Champions.
- 1945 Homestead Grays Negro National League Champions.
- 1945 August Wilson born in Pittsburgh.
- 1946 Louise Whitfield Carnegie dies in New York City June 24.
- 1948 Homestead Grays Negro National League Champions.
- 1951 Father James R. Cox dies March 20.
- 1955 Honus Wagner dies in Carnegie December 6.
- 1960 Bill Mazeroski's home run wins the World Series for the Pittsburgh Pirates, 10-9, against the New York Yankees October 13.
- 1961 Architect Henry Hornbostel dies in Melbourne Beach, Florida December 14.
- 1964 Hill House Association formed from the coming together of The Anna B. Heldman Community Center, Hill City Youth Ministry and Soho Community House.
- 1967 Carnegie Institute of Technology and Mellon Institute unite to form Carnegie Mellon University (CMU).
- 1970 Final game played in Forbes Field June 28. Pittsburgh Pirates vs. Chicago Cubs.
- 1972 Roberto Clemente dies in crash of plane flying relief supplies to victims of Nicaraguan earthquake December 31.
- 1984 Boxer Fritzie Zivic dies May 17.
- 1989 August Wilson wins Pulitzer Prize for Drama for "Fences."
- 1990 August Wilson wins Pulitzer Prize for Drama for "The Piano Lesson."

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